Number of the records: 1
Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities
- 1.0485728 - BFÚ 2018 RIV DE eng J - Journal Article
Hofmanová, Jiřina - Slavík, J. - Ovesná, P. - Tylichová, Zuzana - Vondráček, Jan - Straková, Nicol - Vaculová, Alena - Cigánek, M. - Kozubík, Alois - Knopfová, L. - Šmarda, J. - Machala, M.
Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities.
European Journal of Nutrition. Roč. 56, č. 4 (2017), s. 1493-1508. ISSN 1436-6207. E-ISSN 1436-6215
R&D Projects: GA ČR GA13-09766S; GA MZd(CZ) NV15-30585A
Institutional support: RVO:68081707
Keywords : docosahexaenoic acid * cancer-cells * epithelial-cells
OECD category: Oncology
Impact factor: 4.423, year: 2017
Although beneficial effects of the dietary n-3 docosahexaenoic acid (DHA) or butyrate in colon carcinogenesis have been implicated, the mechanisms of their action are not fully clear. Here, we investigated modulations of composition of individual phospholipid (PL) classes, with a particular emphasis on cardiolipins (CLs), in colon cells treated with DHA, sodium butyrate (NaBt), or their combination (DHA/NaBt), and we evaluated possible associations between lipid changes and cell fate after fatty acid treatment.
Permanent Link: http://hdl.handle.net/11104/0280680
Number of the records: 1