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Vibrations of microtubules: Physics that has not met biology yet
- 1.0484856 - ÚFE 2018 RIV NL eng J - Journal Article
Kučera, Ondřej - Havelka, Daniel - Cifra, Michal
Vibrations of microtubules: Physics that has not met biology yet.
Wave Motion. Roč. 72, 1 July (2017), s. 13-22. ISSN 0165-2125. E-ISSN 1878-433X
R&D Projects: GA ČR(CZ) GA15-17102S
Grant - others:AV ČR(CZ) SAV-15-22
Program: Bilaterální spolupráce
Institutional support: RVO:67985882
Keywords : Models * Vibrations * Microtubules
OECD category: Biophysics
Impact factor: 1.723, year: 2017
There has been extensive study on the vibration dynamics and fluctuations of microtubules in the quest for understanding the relation between microtubule material properties and their ability to carry out several functions in cells. While experimental fluctuation analysis of microtubules has provided an important piece of knowledge about microtubule mechanics, models of microtubule vibrations struggle with providing experimentally testable and biologically relevant predictions. In this mini-review, we critically analyze models of microtubule vibration dynamics, mainly focusing on limitations of particular modeling approaches and their relevance to observed and hypothesized biological phenomena. We assess the possibility of coherent microtubule vibrations in vivo, which is the corner-stone of hypotheses about cellular electromagnetic activity, and we discuss experimental approaches which could resolve controversies about microtubule vibrations
Permanent Link: http://hdl.handle.net/11104/0279993
Number of the records: 1