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Letter to the Editor. Acetic acid is elevated in the exhaled breath of cystic fibrosis patients
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SYSNO ASEP 0484021 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve SCOPUS Title Letter to the Editor. Acetic acid is elevated in the exhaled breath of cystic fibrosis patients Author(s) Španěl, Patrik (UFCH-W) RID, ORCID
Sovová, Kristýna (UFCH-W) RID
Dryahina, Kseniya (UFCH-W) RID, ORCID
Doušová, T. (CZ)
Dřevínek, P. (CZ)
Smith, D. (GB)Source Title Journal of Cystic Fibrosis. - : Elsevier - ISSN 1569-1993
Roč. 16, č. 5 (2017), e17-e18Number of pages 2 s. Language eng - English Country NL - Netherlands Keywords acetic acid ; cystic fibrosis transmembrane conductance regulator ; volatile organic compound Subject RIV CB - Analytical Chemistry, Separation OECD category Analytical chemistry R&D Projects GA14-14534S GA ČR - Czech Science Foundation (CSF) Institutional support UFCH-W - RVO:61388955 EID SCOPUS 85012878379 DOI 10.1016/j.jcf.2017.02.001 Annotation Breath analysis is becoming an attractive non-invasive aid to
clinical diagnosis and therapeutic monitoring and can provide
more insight into pathology of cystic fibrosis (CF) and related
respiratory infections. Selected ion flow tube mass spectrometry,
SIFT-MS [1] allows the analysis of single breath
exhalations on line and also by the off-line analysis of breath
samples collected into bags. SIFT-MS breath analysis has been
directed previously towards identification of volatile biomarkers
of bacterial infection, including Pseudomonas
aeruginosa that commonly infect the lungs of CF patients.
Thus, hydrogen cyanide, HCN, has been identified as a breath
metabolite compound specific (99%) to P. aeruginosa [2].Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2018
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