0469054 - ÚEM 2018 RIV GB eng J - Journal Article
Vysloužilová, L. - Buzgo, Matej - Pokorný, P. - Chvojka, J. - Míčková, Andrea - Klusáček Rampichová, Michala - Kula, J. - Pejchar, K. - Bílek, M. - Lukáš, D. - Amler, Evžen
Needleless coaxial electrospinning: A novel approach to mass production of coaxial nanofibers.
International Journal of Pharmaceutics. Roč. 516, 1-2 (2017), s. 293-300. ISSN 0378-5173. E-ISSN 1873-3476
R&D Projects: GA ČR(CZ) GA15-15697S; GA MŠMT(CZ) LO1508; GA MŠMT(CZ) LO1309
Institutional support: RVO:68378041
Keywords : core-shell nanofibers * coaxial electrospinning * needleless electrospinning
OECD category: Nano-materials (production and properties)
Impact factor: 3.862, year: 2017 ; AIS: 0.71, rok: 2017
DOI: https://doi.org/10.1016/j.ijpharm.2016.11.034

Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering. (C) 2016 Elsevier B.V. All rights reserved.
Permanent Link: http://hdl.handle.net/11104/0268671