0467278 - ÚIACH 2017 SG eng A - Abstract
Mikuška, Pavel - Večeřa, Zbyněk - Buchtová, Marcela - Dumková, J. - Vrlíková, Lucie - Putnová, Barbora - Dočekal, Bohumil - Čapka, Lukáš - Coufalík, Pavel - Křůmal, Kamil - Fictum, P. - Hampl, A.
Intracellular fate of inhaled cadmium oxide nanoparticles and their effect on target organs of mice.
11. th International Particle Toxicology Conference. Book of Abstracts. 2016. s. 124-124.
[International Particle Toxicology Conference /11./. 26.09.2016-30.09.2016, Singapore]
R&D Projects: GA ČR(CZ) GAP503/11/2315; GA ČR(CZ) GBP503/12/G147; GA ČR(CZ) GA14-25558S
Institutional support: RVO:68081715 ; RVO:67985904
Keywords : nanoparticles * inhalation * mice
Subject RIV: CB - Analytical Chemistry, Separation; EB - Genetics ; Molecular Biology (UZFG-Y)

Contribution summarizes findings obtained during inhalation experiments performed with mice for 6 weeks. Inhalation of CdO nanoparticles results in their accumulation not only in the organ of entry, the lungs, but they were also transported by blood to other organs causing serious damage at tissue as well as at cellular level. The exposure to high doses of such nanoparticles leads to complex symptoms affecting the entire body.
Permanent Link: http://hdl.handle.net/11104/0265415