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Solid-state NMR studies of nucleic acid components
- 1.0443272 - ÚOCHB 2016 RIV GB eng J - Journal Article
Dračínský, Martin - Hodgkinson, P.
Solid-state NMR studies of nucleic acid components.
RSC Advances. Roč. 5, č. 16 (2015), s. 12300-12310. ISSN 2046-2069. E-ISSN 2046-2069
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : NMR spectroscopy * nucleic acids * solid-state NMR
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 3.289, year: 2015
http://pubs.rsc.org/en/content/articlepdf/2015/ra/c4ra14404j
Recent applications of solid-state NMR to the characterisation of nucleic acid systems are reviewed. Developments in NMR methodology and DFT-based first-principles calculations have led to the emergence of "NMR crystallography", where solid-state NMR provides information on local structure and dynamics that complements information on periodic ordering and overall structure provided by traditional diffraction crystallography. The solid-state NMR is shown to provide direct information on hydrogen-bonding arrangements, metal ion interactions and local molecular dynamics that is difficult to obtain by other techniques, including solution-state NMR.
Permanent Link: http://hdl.handle.net/11104/0246058
Number of the records: 1