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Obesity-related hypertension: possible pathophysiological mechanisms
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SYSNO ASEP 0437846 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Obesity-related hypertension: possible pathophysiological mechanisms Author(s) Vaněčková, Ivana (FGU-C) RID, ORCID
Maletínská, Lenka (UOCHB-X) RID, ORCID
Behuliak, Michal (FGU-C) RID, ORCID
Nagelová, Veronika (UOCHB-X) RID, ORCID
Zicha, Josef (FGU-C) RID, ORCID, SAI
Kuneš, Jaroslav (FGU-C) RID, ORCIDSource Title Journal of Endocrinology. - : BioScientifica - ISSN 0022-0795
Roč. 223, č. 3 (2014), R63-R78Number of pages 16 s. Language eng - English Country GB - United Kingdom Keywords obesity ; hypertension ; sympathetic nervous system ; renin-angiotensin system ; critical developmental periods ; epigenetics ; rat Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects GAP304/12/0259 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 ; UOCHB-X - RVO:61388963 UT WOS 000345292500002 EID SCOPUS 84911972641 DOI https://doi.org/10.1530/JOE-14-0368 Annotation This review deals with potential pathogenetic mechanisms contributing to obesity-related hypertension, such as hyperinsulinemia, renin-angiotensin system, sympathetic nervous system, adipokines, together with epigenetic mechanisms and environmental factors. Special attention is given to the age factor (critical developmental period) for the development of obesity Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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