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Metallization of Single-Stranded Polyl by Zn2+ Ions in Neutral Solutions
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SYSNO ASEP 0437094 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Metallization of Single-Stranded Polyl by Zn2+ Ions in Neutral Solutions Author(s) Sorokin, V. A. (UA)
Valeev, V. A. (UA)
Usenko, E. L. (UA)
Andrushchenko, Valery (UOCHB-X) RID, ORCIDNumber of authors 4 Source Title Journal of Physical Chemistry B. - : American Chemical Society - ISSN 1520-6106
Roč. 118, č. 43 (2014), s. 12360-12365Number of pages 6 s. Language eng - English Country US - United States Keywords nucleic acid metallization ; zinc ion ; differential UV spectroscopy Subject RIV CF - Physical ; Theoretical Chemistry Institutional support UOCHB-X - RVO:61388963 UT WOS 000344135700006 EID SCOPUS 84908530235 DOI https://doi.org/10.1021/jp5065903 Annotation Metallization of single-stranded polyinosinic acid (polyI) by Zn2+ ions at pH 7.0 was studied by differential UV spectroscopy at different temperatures. It was found that polyI is metallized at N7 and N1 atoms of hypoxanthine. The concentration dependence of the degree of binding of Zn2+ ions to both N7 and N1 sites was obtained, and the corresponding binding constants were determined. Metallization of N1 occurs due to Zn2+ substituting the imino protons and is effective not only at alkaline but also at neutral pH. This makes multistranded polyI-based systems more promising candidates for use in nanoelectronics than natural DNA sequences, metallization of which can be achieved only at alkaline pH. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2015
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