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Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS
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SYSNO ASEP 0435204 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS Author(s) Viero, C. (DE)
Forostyak, Oksana (UEM-P)
Syková, Eva (UEM-P) RID
Dayanithi, Govindan (UEM-P) RIDSource Title Frontiers in Cell and Developmental Biology. - : Frontiers Research Foundation - ISSN 2296-634X
-, č. 2 (2014), s. 36Number of pages 7 s. Language eng - English Country CH - Switzerland Keywords human embryonic stem sell ; neural precursors ; neurodegenerative diseases Subject RIV FH - Neurology R&D Projects GAP304/11/2373 GA ČR - Czech Science Foundation (CSF) GAP304/11/0184 GA ČR - Czech Science Foundation (CSF) GBP304/12/G069 GA ČR - Czech Science Foundation (CSF) EE2.3.20.0274 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEM-P - RVO:68378041 DOI https://doi.org/10.3389/fcell.2014.00036 Annotation We gather results from our previous studies and present a cell model that was successfully used in functional analyses and engraftment experiments. These neuronal precursors exhibit spontaneous and evoked activity, indicating that their electrophysiological and calcium handling properties are similar to those of matured neurons. Hence this summarized information will serve as a basis to design better stem cell-based therapies to improve neural regeneration. Workplace Institute of Experimental Medicine Contact Arzuv Čaryjeva, arzuv.caryjeva@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2015
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