Number of the records: 1
Polylactide nanofibers with hydroxyapatite as growth substrates for osteoblast-like cells
- 1.0434268 - FGÚ 2015 RIV US eng J - Journal Article
Novotná, Katarína - Zajdlová, Martina - Suchý, Tomáš - Hadraba, Daniel - Lopot, F. - Žaloudková, Margit - Douglas, T.E.L. - Munzarová, M. - Juklíčková, M. - Stránská, D. - Kubies, Dana - Schaubroeck, D. - Wille, S. - Balcaen, L. - Jarošová, Markéta - Kozak, Halyna - Kromka, Alexander - Švindrych, Zdeněk - Lisá, Věra - Balík, Karel - Bačáková, Lucie
Polylactide nanofibers with hydroxyapatite as growth substrates for osteoblast-like cells.
Journal of Biomedical Materials Research. Part A. Roč. 102, č. 11 (2014), s. 3918-3930. ISSN 1549-3296. E-ISSN 1552-4965
R&D Projects: GA ČR(CZ) GA106/09/1000; GA ČR(CZ) GAP108/10/1106
Institutional support: RVO:67985823 ; RVO:61389013 ; RVO:67985891 ; RVO:68378271
Keywords : electrospinning * nanofibers * polyactide * hydroxyapatite
Subject RIV: EI - Biotechnology ; Bionics; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 3.369, year: 2014
The nanofibrous PLA scaffolds enriched with 5 or 15 wt % of HA provided a good support for the adhesion, growth, and osteogenic diferentiation of human osteoblast-like MG 63 cells. At the same time, no significant immune activation of the macrophage-like RAW 264.7 cells cultivated on the tested scaffolds was observed. Thus, these scaffolds are promising as cell carriers for bone tissue engineering, particularly in non-load-bearing applications
Permanent Link: http://hdl.handle.net/11104/0238362
Number of the records: 1