Thermodynamic and structural analysis of HIV protease resistance to darunavir - analysis of heavily mutated patient- derived HIV-1 proteases

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SYSNO	0427922
Title	Thermodynamic and structural analysis of HIV protease resistance to darunavir - analysis of heavily mutated patient- derived HIV-1 proteases
Author(s)	Kožíšek, Milan (UOCHB-X) [220/22]_{RID, ORCID} Lepšík, Martin (UOCHB-X) [610/61]_{RID, ORCID} Grantz Šašková, Klára (UOCHB-X) [220/22]_{RID, ORCID} Brynda, Jiří (UMG-J) [31]_RID Konvalinka, Jan (UOCHB-X) [220/22]_{RID, ORCID} Řezáčová, Pavlína (UOCHB-X) [930/93]_{RID, ORCID}
Corespondence/senior	Konvalinka, Jan - Korespondující autor
Source Title	FEBS Journal. Roč. 281, č. 7 (2014), s. 1834-1847
Document Type	Článek v odborném periodiku
Grant	GAP207/11/1798 GA ČR - Czech Science Foundation (CSF)
	CZ.2.16/3.1.00/24016, XE - EU countries
Institutional support	UOCHB-X - RVO:61388963 ; UMG-J - RVO:68378050
Language	eng
Country	GB
Keywords	enthropic contribution * HIV protease inhibitors * isothermal titration calorimetry * resistance mutation * X-ray crystallography
Cooperating institutions	Karlova Univerzita v Praze (Czech Republic)
Permanent Link	http://hdl.handle.net/11104/0233503

Number of the records: 1