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Genomics of introgression across a species barrier: Half a Million SNPs across the European house mouse hybrid zone
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SYSNO ASEP 0392831 Document Type A - Abstract R&D Document Type The record was not marked in the RIV R&D Document Type Není vybrán druh dokumentu Title Genomics of introgression across a species barrier: Half a Million SNPs across the European house mouse hybrid zone Author(s) Baird, Stuart J. E. (UBO-W) RID, ORCID, SAI
Macholán, Miloš (UZFG-Y) RID, ORCID
Munclinger, P. (CZ)
Piálek, Jaroslav (UBO-W) RID, ORCID, SAINumber of authors 4 Source Title Speciation 2013. - Montpellier, 2013 Number of pages 1 s. Publication form Online - E Action European Conference on Speciation Research /2./ Event date 27.05.2013-29.05.2013 VEvent location Montpellier Country FR - France Event type EUR Language eng - English Country FR - France Keywords European House Mouse hybrid zone Subject RIV EG - Zoology Institutional support UBO-W - RVO:68081766 Annotation Understanding speciation as a birth-death process requires study not only of the maintenance of species barriers, but also of those forces acting to break them down ("speciation genes" and "anti-speciation" genes). We use the European House Mouse hybrid zone as a natural experiment to examine such forces. When SNP marker data is dense on the recombination map it cannot be treated as a series of independent loci but can, instead and more naturally, be analysed in terms of Fisher’s representation of the outcome of admixture and recombination: the ancestral source of blocks of DNA along the genome and the position of junctions (arising from recombination) where that source state changes. Cascades in the size of blocks allow ancestral polymorphism to be distinguished from introgression polymorphism. Frequency spectra of introgressed block sizes allow inference of the time since secondary contact. Geographic outlier analysis of blocks allow regions of the genome associated with the introgression of "antispeciation" genes across the species barrier to be identified. These insights increase our understanding not only of the mouse species barrier, but also how it can decay in its natural setting. Workplace Institute of Vertebrate Biology Contact Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Year of Publishing 2014
Number of the records: 1