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Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyi
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SYSNO ASEP 0387863 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyi Author(s) Hroudová, Miluše (UMG-J) RID
Vojta, Petr (UMG-J)
Strnad, Hynek (UMG-J) RID
Krejčík, Zdeněk (UMG-J)
Rídl, Jakub (UMG-J) ORCID
Pačes, Jan (UMG-J) RID, ORCID
Vlček, Čestmír (UMG-J) RID
Pačes, Václav (UMG-J) RIDSource Title PLoS ONE. - : Public Library of Science - ISSN 1932-6203
Roč. 7, č. 4 (2012), e36420Number of pages 11 s. Publication form Online - E Language eng - English Country US - United States Keywords homeobox genes ; cnidarian genome ; sensory organs Subject RIV EB - Genetics ; Molecular Biology R&D Projects 1M0520 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000305340200078 DOI https://doi.org/10.1371/journal.pone.0036420 Annotation Formation of all metazoan bodies is controlled by a group of selector genes including homeobox genes, highly conserved across the entire animal kingdom. The homeobox genes from Pou and Six classes are key members of the regulation cascades determining development of sensory organs, nervous system, gonads and muscles. Besides using common bilaterian models, more attention has recently been targeted at the identification and characterization of these genes within the basal metazoan phyla. Cnidaria as a diploblastic sister group to bilateria with simple and yet specialized organs are suitable models for studies on the sensory organ origin and the associated role of homeobox genes. In this work, Pou and Six homeobox genes, together with a broad range of other sensory-specific transcription factors, were identified in the transcriptome of hydrozoan jellyfish Craspedacusta sowerbyi. Phylogenetic analyses of Pou and Six proteins revealed cnidarian-specific sequence motifs and contributed to the classification of individual factors. The majority of the Craspedacusta sowerbyi Pou and Six homeobox genes are predominantly expressed in statocysts, manubrium and nerve ring, the tissues with sensory and nervous activities. The described diversity and expression patterns of Pou and Six factors in hydrozoan jellyfish highlight their evolutionarily conserved functions. This study extends the knowledge of the cnidarian genome complexity and shows that the transcriptome of hydrozoan jellyfish is generally rich in homeodomain transcription factors employed in the regulation of sensory and nervous functions. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2013
Number of the records: 1