0379146 - BFÚ 2013 RIV US eng J - Journal Article
Betanzos-Lara, S. - Salassa, L. - Habtemariam, A. - Nováková, Olga - Pizarro, A.M. - Clarkson, G.J. - Lišková, Barbora - Brabec, Viktor - Sadler, P.J.
Photoactivatable organometallic pyridyl ruthenium(II) arene complexes.
Organometallics. Roč. 31, č. 9 (2012), s. 3466-3479. ISSN 0276-7333. E-ISSN 1520-6041
R&D Projects: GA ČR(CZ) GD301/09/H004
Institutional research plan: CEZ:AV0Z50040702
Keywords : ruthenium(II) arene complexes * photochemotherapy * DNA binding
Subject RIV: BO - Biophysics
Impact factor: 4.145, year: 2012
DOI: https://doi.org/10.1021/om201177y

Photoactivatable Organometallic pyridyl ruthenium(II) arene complexes can selectively photodissociate the monodentate ligand when excited with UVA or white light, allowing strict control of the formation of the reactive aqua species. Calf thymus (CT)-DNA binding studies showed that the irradiated complexes bind to CT-DNA, whereas the nonirradiated forms bind negligibly.

Permanent Link: http://hdl.handle.net/11104/0210410