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Gene and Cardivascular Function
- 1.0371679 - FGÚ 2012 RIV US eng M - Monography Chapter
Kuneš, Jaroslav - Kadlecová, Michaela - Zicha, Josef
Gene-Environment Interactions: Their Role in Hypertension Development.
Gene and Cardivascular Function. New York: Springer, 2011 - (Ošťádal, B.; Nagano, M.; Dhalla, N.), s. 177-184. ISBN 978-1-4419-7206-4
R&D Projects: GA MŠMT(CZ) 1M0510; GA ČR(CZ) GA305/09/0336; GA AV ČR(CZ) IAA500110902
Institutional research plan: CEZ:AV0Z50110509
Keywords : critical developmental periods * dietary interventions * epigenetics
Subject RIV: ED - Physiology
The interactions of multiple genetic and environmental factors as well as gene-gene interactions cause modifications of various systems that adjust blood pressure to actual living conditions. Numerous environmental factors could modify the development of organism not only by the influence on the expression of genetic information but mainly by epigenetic influence It is difficult to identify all genetic determinants leading to hypertension and other cardiovascular diseases because they become a medical problem in adulthood, although their roots might be traced back to earlier stage sof ontogeny. The link between distinct developmental periods involves the changes in genetic expression including epigenetic phenomena
Permanent Link: http://hdl.handle.net/11104/0205149
Number of the records: 1