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Hepatoprotective effect of curcumin in lipopolysaccharide/D-galactosamine model of liver injury in rats: Relationship to HO-1/CO antioxidant system
- 1.0368217 - ÚEM 2012 RIV IT eng J - Journal Article
Černý, D. - Lekič, N. - Váňová, K. - Muchová, L. - Hořínek, A. - Kmoníčková, Eva - Zídek, Zdeněk - Kameníková, L. - Farghali, H.
Hepatoprotective effect of curcumin in lipopolysaccharide/D-galactosamine model of liver injury in rats: Relationship to HO-1/CO antioxidant system.
Fitoterapia. Roč. 82, č. 5 (2011), s. 786-791. ISSN 0367-326X. E-ISSN 1873-6971
R&D Projects: GA ČR GA305/07/0061
Grant - others:GA ČR(CZ) GA305/09/0004
Institutional research plan: CEZ:AV0Z50390512
Keywords : Curcumin * Heme oxygenase-1 * Carbon monoxide
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 1.848, year: 2011
Curcumin possesses hepatoprotective and anti-fibrotic effects. The results suggest that the protective activity of this compound depends on activity of the enzyme heme oxygenase-1 and on formation of karbon monoxide.
Permanent Link: http://hdl.handle.net/11104/0202618
Number of the records: 1