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Excitation Specificity of Repolarization Parameters
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SYSNO ASEP 0368135 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Excitation Specificity of Repolarization Parameters Author(s) Halámek, Josef (UPT-D) RID, ORCID, SAI
Jurák, Pavel (UPT-D) RID, ORCID, SAI
Vondra, Vlastimil (UPT-D) RID, ORCID, SAI
Viščor, Ivo (UPT-D) RID, ORCID, SAI
Plachý, M. (CZ)
Leinveber, P. (CZ)Number of authors 6 Source Title 33rd Annual International IEEE EMBS Conference. - Piscataway : IEEE, 2011 - ISSN 1557-170X - ISBN 978-1-4244-4122-8 Pages s. 961-964 Number of pages 4 s. Action Annual International IEEE EMBS Conference /33./ Event date 30.08.2011-03.09.2011 VEvent location Boston Country US - United States Event type WRD Language eng - English Country US - United States Keywords cardiovascular signal processing ; ventricular models ; ventricular arrhythmia mechanisms Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects ME09050 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z20650511 - UPT-D (2005-2011) UT WOS 000298810001027 Annotation The excitation specificity of QT dynamic parameters was tested on three groups of subjects: healthy subjects; non-medicated hypertensive subjects with metabolic syndrome; and subjects with essential hypertension. Four different excitations of RR were used: bicycling exercise; tilt with breathing 0.1 and 0.33 Hz; and deep breathing. Linear dynamic feedback model of QT/RR coupling was supposed at the analysis and next repolarization parameters were tested: QTc; gain of QT/RR coupling for slow and fast RR variability; time constant of QT adaptation; and random QT variability. Results: Dynamic repolarization parameters statistically significantly depend on the type of RR excitation. The gain of QT/RR coupling for slow RR variability, the time constant of QT adaptation and QTc are maximal at RR excitation given by the bicycling exercise. The frequency of breathing, i.e. corresponding vagal modulation has no effect on repolarization parameters. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2012
Number of the records: 1