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Transcriptome alterations in maternal and fetal cells induced by tobacco smoke
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SYSNO ASEP 0365848 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Transcriptome alterations in maternal and fetal cells induced by tobacco smoke Author(s) Votavová, H. (CZ)
Dostálová-Merkerová, M. (CZ)
Fejglová, K. (CZ)
Vašíková, A. (CZ)
Krejčík, Z. (CZ)
Pastorková, Anna (UEM-P) RID
Tabashidze, Nana (UEM-P)
Topinka, Jan (UEM-P) RID, ORCID
Veleminský Jr., M. (CZ)
Šrám, Radim (UEM-P) RID
Brdička, R. (CZ)Source Title Placenta. - : Elsevier - ISSN 0143-4004
Roč. 32, č. 10 (2011), s. 763-770Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords maternal smoking ; placenta ; cord blood Subject RIV FP - Other Medical Disciplines R&D Projects 2B06088 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000295749900009 EID SCOPUS 80052927224 DOI 10.1016/j.placenta.2011.06.022 Annotation The study demonstrated that maternal smoking causes significant changes in transcriptome of placental and fetal cells which deregulate numerous biological processes important for growth and development of the fetus. An activation of fetal CYP genes showed a limited ability of the placenta to modulate toxic effects of maternal tobacco use. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2012
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