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Functional inactivation of the rat hippocampus disrupts avoidance of a moving object

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    0364564 - FGÚ 2012 RIV US eng J - Journal Article
    Telenský, P. - Svoboda, Jan - Blahna, Karel - Bureš, Jan - Kubík, Štěpán - Stuchlík, Aleš
    Functional inactivation of the rat hippocampus disrupts avoidance of a moving object.
    Proceedings of the National Academy of Sciences of the United States of America. Roč. 108, č. 13 (2011), s. 5414-5418. ISSN 0027-8424. E-ISSN 1091-6490
    R&D Projects: GA ČR(CZ) GA309/09/0286; GA ČR(CZ) GCP303/10/J032; GA ČR GPP303/10/P191; GA AV ČR(CZ) KJB500110904; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554; GA ČR(CZ) GD206/05/H012
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : cognitive map * declarative memory * episodic memory * dynamic environments
    Subject RIV: FH - Neurology
    Impact factor: 9.681, year: 2011

    The work shows that avoidance of a visible moving object (a small robot) relies on the hippocampus, an archicortical brain area considered to be crucial for memory and spatial navigation. Navigation with respect to a stable robot did not require hippocampus. Study was done in an original enemy avoidance task, hippocampus was functionally inactivated by stereotaxic injection of tetrodotoxin. The study represents crucial finding extending the cognitive map theory of the hippocampus function
    Permanent Link: http://hdl.handle.net/11104/0200019

     
     
Number of the records: 1  

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