Polymerase synthesis of modified DNA containing cytosine in major groove

Number of the records: 1

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SYSNO ASEP	0361573
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	The record was not marked in the RIV
Title	Polymerase synthesis of modified DNA containing cytosine in major groove
Author(s)	Kielkowski, Pavel (UOCHB-X)_RID Hocek, Michal (UOCHB-X)_{RID, ORCID}
Number of authors	2
Source Title	Chemistry of Nucleic Acid Components. 15th Symposium. - Praha : Institute of Organic Chemistry and Biochemistry AS CR, v. v. i., 2011 / Hocek M. - ISBN 978-80-86241-37-1
Pages	s. 359-360
Number of pages	2 s.
Action	Chemistry of Nucleic Acid Components /15./
Event date	05.06.2011-10.06.2011
VEvent location	Český Krumlov
Country	CZ - Czech Republic
Event type	EUR
Language	eng - English
Country	CZ - Czech Republic
Keywords	DNA ; polymerase ; cytosine
Subject RIV	CC - Organic Chemistry
R&D Projects	LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA203/09/0317 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
Annotation	(Cytosine-5-yl)ethynyl derivatives of pyrimidine and 7-deazaadenine 2-deoxyribonucleosides and nucleoside triphosphates (dNTPs) were prepared by aqueous Sonogashira coupling. All modified dNTPs were excellent substrates for DNA polymerases to give DNA bearing acetylene- linked cytosine(s) in the major groove.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
Year of Publishing	2012

Number of the records: 1