Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone

Wang, L.; Luzynski, K.; Pool, J. E.; Janoušek, V.; Dufková, Petra; Vyskočilová, Martina; Teeter, K. C.; Nachman, M. W.; Munclinger, P.; Macholán, Miloš; Piálek, Jaroslav; Tucker, P. K.

doi:https://dx.doi.org/10.1111/j.1365-294X.2011.05148.x

Number of the records: 1

Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone

1.

SYSNO ASEP	0360252
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone
Author(s)	Wang, L. (US) Luzynski, K. (US) Pool, J. E. (US) Janoušek, V. (CZ) Dufková, Petra (UBO-W)_{RID, SAI} Vyskočilová, Martina (UZFG-Y) Teeter, K. C. (US) Nachman, M. W. (US) Munclinger, P. (CZ) Macholán, Miloš (UZFG-Y)_{RID, ORCID} Piálek, Jaroslav (UBO-W)_{RID, ORCID, SAI} Tucker, P. K. (US)
Number of authors	12
Source Title	Molecular Ecology. - : Wiley - ISSN 0962-1083 Roč. 20, č. 14 (2011), s. 2985-3000
Number of pages	16 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	house mouse ; hybrid zones ; linkage disequilibrium ; SNP markers
Subject RIV	EG - Zoology
R&D Projects	GA206/08/0640 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z60930519 - UBO-W (2005-2011)
	AV0Z50450515 - UZFG-Y (2005-2011)
UT WOS	000292445700011
EID SCOPUS	79960104267
DOI	10.1111/j.1365-294X.2011.05148.x
Annotation	Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here, evidence for movement in the house mouse Mus musculus domesticus x M. m. musculus hybrid zone is provided using measures of LD and haplotype structure among neighbouring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled, and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography-dependent asymmetrical dispersal or selection favouring one subspecies over the other.
Workplace	Institute of Vertebrate Biology
Contact	Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524
Year of Publishing	2012

Number of the records: 1