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Real-time monitoring of biomolecular interactions in blood plasma using surface plasmon resonance
- 1.0356069 - ÚFE 2011 CZ eng A - Abstract
Špringer, Tomáš - Piliarik, Marek - Homola, Jiří
Real-time monitoring of biomolecular interactions in blood plasma using surface plasmon resonance.
EUROPT(R)ODE X. Vol. XConference on Optical Chemical Sensors and Biosensors. Praha: Institute of Photonics and Electronics AS CR, v.v.i, 2010 - (Homola, J.). s. 226-226. ISBN 978-80-86269-20-7.
[EUROPT(R)ODE X – X.Conference on Optical Chemical Sensors and Biosensors. 28.03.2010-31.3.2010, Praha]
R&D Projects: GA AV ČR KAN200670701
Institutional research plan: CEZ:AV0Z20670512
Keywords : surface plasmon resonance * molecular interaction analysis * microfluidics * optical biosensor
Subject RIV: JB - Sensors, Measurment, Regulation
We report a novel approach to biomolecular interaction analysis which allows real-time monitoring of interactions in complex media. The investi¬gated complex sample (e.g. blood plasma) and a washing solution are al¬ternately injected in the flow-chamber of a surface plasmon resonance biosensor. Immediate switching between these liquids and removal of non-specifi¬cally adsorbed material on a chip surface allows assessing the actual level of bound analyte in the course of the binding.
Permanent Link: http://hdl.handle.net/11104/0194689
Number of the records: 1