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Actin complexes in the cell nucleus: new stones in an old field
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SYSNO ASEP 0351361 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Actin complexes in the cell nucleus: new stones in an old field Author(s) Castano, Enrique (UMG-J)
Philimonenko, Vlada (UMG-J)
Kahle, Michal (UMG-J)
Fukalová, Jana (UMG-J)
Kalendová, Alžběta (UMG-J)
Yildirim, Sukriye (UMG-J)
Dzijak, Rastislav (UMG-J) RID
Dingová, Hana (UMG-J)
Hozák, Pavel (UMG-J) RID, ORCIDSource Title Histochemistry and Cell Biology. - : Springer - ISSN 0948-6143
Roč. 133, č. 6 (2010), s. 607-626Number of pages 20 s. Language eng - English Country DE - Germany Keywords RNA polymerase II ; ABL tyrosine kinase ; F-actin Subject RIV EB - Genetics ; Molecular Biology R&D Projects GA204/07/1592 GA ČR - Czech Science Foundation (CSF) GD204/09/H084 GA ČR - Czech Science Foundation (CSF) LC545 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 2B06063 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000277640400001 DOI 10.1007/s00418-010-0701-2 Annotation Actin is a well-known protein that has shown a myriad of activities in the cytoplasm. However, recent findings of actin involvement in nuclear processes are overwhelming. Actin complexes in the nucleus range from very dynamic chromatin-remodeling complexes to structural elements of the matrix with single partners known as actin-binding proteins (ABPs). This review summarizes the recent findings of actin-containing complexes in the nucleus. Particular attention is given to key processes like chromatin remodeling, transcription, DNA replication, nucleocytoplasmic transport and to actin roles in nuclear architecture. Understanding the mechanisms involving ABPs will definitely lead us to the principles of the regulation of gene expression performed via concerting nuclear and cytoplasmic processes. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2011
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