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Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences
- 1.0349459 - ÚBO 2011 RIV US eng J - Journal Article
Drexler, J. F. - Gloza-Rausch, F. - Glende, J. - Corman, V. M. - Muth, D. - Goettsche, M. - Seebens, A. - Niedrig, M. - Pfefferle, S. - Yordanov, S. - Zhelyazkov, L. - Hermanns, U. - Vallo, Peter - Lukashev, A. - Müller, M. A. - Deng, H. - Herrler, G. - Drosten, C.
Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences.
Journal of Virology. Roč. 84, č. 21 (2010), s. 11336-11349. ISSN 0022-538X. E-ISSN 1098-5514
Institutional research plan: CEZ:AV0Z60930519
Keywords : cross-species transmission * SARS-like coronaviruses * reservoir hosts * horseshoe bats
Subject RIV: EE - Microbiology, Virology
Impact factor: 5.189, year: 2010
The paper evaluates coronaviruses (CoV) in rhinolophid and vespertilionid bat species common in Europe. Rhinolophids were shown to carry severe acute respiratory syndrome (SARS)-related CoV at high frequencies and concentrations, as well as two Alphacoronavirus clades Three other CoV clades present in Miniopterus bats in China were also present in European Miniopterus bats. An additional novel Alphacoronavirus clade was detected in Nyctalus leisleri. A CoV grouping criterion was developed by comparing amino acid identities across an 816-bp fragment of the RNA-dependent RNA polymerases of all accepted mammalian CoV species. Strict associations with host bat genera were confirmed for six independent CoV groups represented simultaneously in China and Europe. A SARS-related virus from a Bulgarian specimens of Rhinolophus blasii bat was fully sequenced. This study underlines the importance of assessments of the zoonotic potential of widely distributed bat-borne CoV.
Permanent Link: http://hdl.handle.net/11104/0189694
Number of the records: 1