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Characterization of Ca2+ Signalling in Postnatal Mouse Retinal Ganglion Cells: Involvement of OPA1 in Ca2+ Clearance

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    SYSNO ASEP0349378
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleCharacterization of Ca2+ Signalling in Postnatal Mouse Retinal Ganglion Cells: Involvement of OPA1 in Ca2+ Clearance
    Author(s) Dayanithi, Govindan (UEM-P) RID
    Chen-Kuo-Chang, M. (FR)
    Viero, C. (GB)
    Hamel, C. (FR)
    Muller, A. (FR)
    Lenaers, G. (FR)
    Source TitleOphthalmic Genetics. - : Taylor & Francis - ISSN 1381-6810
    Roč. 31, č. 2 (2010), s. 53-65
    Number of pages13 s.
    Languageeng - English
    CountryUS - United States
    Keywordsretinal ganglion cells ; Ca2+ homeostasis ; Ca2+ clearance
    Subject RIVFH - Neurology
    CEZAV0Z50390703 - UEM-P (2007-2013)
    UT WOS000279009200001
    EID SCOPUS77952223490
    DOI10.3109/13816811003698117
    AnnotationHere we demonstrate an important role of OPA1 in mitochondrial dependent Ca2+ homeostasis and cell survival in RGCs, suggesting a possible pathophysiological mechanism involved in inherited optic neuropathies
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2011
Number of the records: 1  

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