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Role of the Transmembrane Potential in the Membrane Proton Leak
- 1.0345906 - FGÚ 2011 RIV US eng J - Journal Article
Ruprecht, A. - Sokolenko, E. A. - Beck, V. - Ninnemann, O. - Jabůrek, Martin - Trimbuch, T. - Klishin, S. S. - Ježek, Petr - Skulachev, V. P. - Pohl, E. E.
Role of the Transmembrane Potential in the Membrane Proton Leak.
Biophysical Journal. Roč. 98, č. 8 (2010), s. 1503-1511. ISSN 0006-3495. E-ISSN 1542-0086
R&D Projects: GA MŠMT ME09018; GA ČR(CZ) GA303/07/0105
Institutional research plan: CEZ:AV0Z50110509
Keywords : proton leak * membrane potential * uncoupling proteins
Subject RIV: BO - Biophysics
Impact factor: 4.218, year: 2010
This study investigates the role of transmembrane potential using planar lipid membranes reconstituted with purified uncoupling proteins (UCPs) and/or unsaturated fatty acids. We show that high membrane potential significantly promotes the protonophoric function of UCPs in the presence of fatty acids
Permanent Link: http://hdl.handle.net/11104/0187078
Number of the records: 1