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Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats
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SYSNO ASEP 0341807 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats Author(s) Mareš, Pavel (FGU-C) RID, ORCID
Stehlíková, M. (CZ)Source Title Neuroscience Letters. - : Elsevier - ISSN 0304-3940
Roč. 469, č. 3 (2010), s. 396-399Number of pages 4 s. Language eng - English Country IE - Ireland Keywords ganaxolone ; epileptic seizures ; motor abilities Subject RIV FH - Neurology R&D Projects LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA203/06/1605 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000274722100024 DOI 10.1016/j.neulet.2009.12.037 Annotation Anticonvulsant activity of ganaxolone against cortical epileptic afterdischarges was demonstrated in 12-, 18- and 25-day-old rats. The effective doses (20 and 40 mg/kg) did not significantly affected motor performance of the same age groups of rats Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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