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CXC and CC chemokines induced in human renal epithelial cells by inflammatory cytokines
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SYSNO ASEP 0341403 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title CXC and CC chemokines induced in human renal epithelial cells by inflammatory cytokines Author(s) Thornburn, E. (CZ)
Kolesar, L. (CZ)
Brabcová, E. (CZ)
Petříčková, Kateřina (MBU-M) RID
Petříček, Miroslav (MBU-M) RID
Jarešová, M. (CZ)
Slavcev, A. (CZ)
Stříž, I. (CZ)Source Title Acta Pathologica Microbiologica et Immunologica Scandinavica - ISSN 0903-4641
Roč. 117, č. 7 (2009), s. 477-487Number of pages 11 s. Language eng - English Country US - United States Keywords Epithelial cells ; chemokines ; transplantation Subject RIV EE - Microbiology, Virology CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000267315400001 DOI 10.1111/j.1600-0463.2009.02446.x Annotation Human renal epithelial cells might play an important role during the allograft rejection by producing chemokines in response to proinflammatory cytokines such as tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 beta produced by endothelial and epithelial cells early after transplantation. The production of chemokines allows inflammatory cells to be drawn into the kidney graft and therefore plays a critical role in the pathophysiologic processes that lead to the rejection of renal transplant. In this process, two chemokine superfamilies, the CC and the CXC chemokines, are the most important Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2010
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