Automated Ambient Desorption-Ionization Platform for Surface Imaging Integrated with a Commercial Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

Pól, Jaroslav; Vidová, Veronika; Kruppa, G.; Kobliha, Václav; Novák, Petr; Lemr, Karel; Kotiaho, T.; Kostiainen, R.; Havlíček, Vladimír; Volný, Michael

doi:https://dx.doi.org/10.1021/ac901368q

Number of the records: 1

Automated Ambient Desorption-Ionization Platform for Surface Imaging Integrated with a Commercial Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

1.

SYSNO ASEP	0340257
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Automated Ambient Desorption-Ionization Platform for Surface Imaging Integrated with a Commercial Fourier Transform Ion Cyclotron Resonance Mass Spectrometer
Author(s)	Pól, Jaroslav (MBU-M) Vidová, Veronika (MBU-M) Kruppa, G. (US) Kobliha, Václav (MBU-M) Novák, Petr (MBU-M)_{RID, ORCID} Lemr, Karel (MBU-M)_{RID, ORCID} Kotiaho, T. (FI) Kostiainen, R. (FI) Havlíček, Vladimír (MBU-M)_{RID, ORCID} Volný, Michael (MBU-M)_ORCID
Source Title	Analytical Chemistry. - : American Chemical Society - ISSN 0003-2700 Roč. 81, č. 20 (2009), s. 8479-8487
Number of pages	9 s.
Language	eng - English
Country	US - United States
Keywords	ATMOSPHERIC-PRESSURE PHOTOIONIZATION ; COMPREHENSIVE CLASSIFICATION-SYSTEM ; mass spectrometry
Subject RIV	EE - Microbiology, Virology
R&D Projects	LC07017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000270670600028
DOI	10.1021/ac901368q
Annotation	A fully automated atmospheric pressure ionization platform has been built and coupled with a commercial high-resolution Fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS) instrument. The outstanding performance of this instrument allowed screening on the basis of exact masses in imaging mode. The main novel aspect was in the integration of the atmospheric pressure ionization imaging into the current software for matrix-assisted laser desorption ionization (MALDI) imaging, which allows the user of this commercial dual-source mass spectrometer to perform MALDI-MS and different ambient MS imaging from the same user interface and to utilize the same software tools. Desorption electrospray ionization (DESI) and desorption atmospheric pressure photoionization (DAPPI) were chosen to test the ambient surface imaging capabilities of this new ionization platform
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2010

Number of the records: 1