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TMEM70 protein — A novel ancillary factor of mammalian ATP synthese
- 1.0338634 - FGÚ 2010 RIV NL eng J - Journal Article
Houštěk, Josef - Kmoch, S. - Zeman, J.
TMEM70 protein — A novel ancillary factor of mammalian ATP synthese.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1787, č. 5 (2009), s. 529-532. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA MŠMT(CZ) 1M0520; GA MZd(CZ) NS9759
Institutional research plan: CEZ:AV0Z50110509
Keywords : ATP synthase * disease * TMEM70
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.688, year: 2009
Mutations in TMEM70 gene encoding a 30kD mitochondrial protein of unknown function prevent ATP synthase biogenesis and are found in most known patients with mitochondrial disease due to decreased ATP synthase content. TMEM70 represents a new ancillary factor of mammalian ATP synthase. As revealed by phylogenetic analysis, TMEM70 is specific for higher eukaryotes
Permanent Link: http://hdl.handle.net/11104/0182358
Number of the records: 1