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Ion specific effects of sodium and potassium on the catalytic activity of HIV-1 protease

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    0336385 - ÚOCHB 2010 RIV GB eng J - Journal Article
    Heyda, Jan - Pokorná, Jana - Vrbka, Luboš - Vácha, Robert - Jagoda-Cwiklik, B. - Konvalinka, Jan - Jungwirth, Pavel - Vondrášek, Jiří
    Ion specific effects of sodium and potassium on the catalytic activity of HIV-1 protease.
    Physical Chemistry Chemical Physics. Roč. 11, č. 35 (2009), s. 7599-7604. ISSN 1463-9076. E-ISSN 1463-9084
    R&D Projects: GA MŠMT LC512; GA MŠMT 1M0508; GA ČR GA203/08/0114; GA ČR GA203/06/1727
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : HIV-1 protease * ion-protein interaction * Hofmeister series
    Subject RIV: CE - Biochemistry
    Impact factor: 4.116, year: 2009

    This paper describes cation-specific effects on the enzymatic activity of HIV-1 protease. The behavior of this enzyme in aqueous NaCl and KCl solutions is investigated by kinetic measurements and molecular dynamics simulations.
    Permanent Link: http://hdl.handle.net/11104/0180627

     
     
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