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Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin
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SYSNO ASEP 0334046 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin Author(s) Katsetos, C.D. (US)
Dráberová, Eduarda (UMG-J) RID, ORCID
Legido, A. (US)
Dumontet, C. (FR)
Dráber, Pavel (UMG-J) RID, ORCIDNumber of authors 5 Source Title Journal of Cellular Physiology. - : Wiley - ISSN 0021-9541
Roč. 221, č. 3 (2009), s. 505-513Number of pages 9 s. Language eng - English Country US - United States Keywords Beta-II-tubulin ; glioblastoma Subject RIV EB - Genetics ; Molecular Biology R&D Projects KAN200520701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000271540100002 DOI 10.1002/jcp.21870 Annotation This minireview focuses on microtubules and tubulin as emerging targets in potential therapy of GBM using a new class of betaIII-tubulin-targeted drugs in the light of recent developments concerning the function and potential role of this isotype in clinically aggressive tumor behavior, cancer stem cells, tumor hypoxia and chemoresistance to tubulin binding agents, principally taxanes. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2010
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