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Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances
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SYSNO ASEP 0332654 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances Author(s) Balšánek, V. (CZ)
Tichotová, L. (CZ)
Kuneš, J. (CZ)
Špulák, M. (CZ)
Pour, M. (CZ)
Votruba, Ivan (UOCHB-X) RID
Buchta, V. (CZ)Number of authors 7 Source Title Collection of Czechoslovak Chemical Communications. - : Ústav organické chemie a biochemie AV ČR, v. v. i. - ISSN 0010-0765
Roč. 74, 7/8 (2009), s. 1161-1178Number of pages 18 s. Language eng - English Country CZ - Czech Republic Keywords Pd catalysis ; Cross-coupling reactions ; heterocycles ; tetrazoles Subject RIV CC - Organic Chemistry R&D Projects 1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000269891900011 DOI 10.1135/cccc2009040 Annotation A series of tetrazoles linked to the butenolide core via benzene rings were prepared by the Stille coupling reaction of alpha-(tributylstannyl)butenolides and 5-(alkylsulfanyl)-1-(4-iodophenyl)tetrazoles, and the compounds were tested for antifungal and cytostatic activity. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2010
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