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Genetic variation in adipokine genes and risk of colorectal cancer
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SYSNO ASEP 0331378 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Genetic variation in adipokine genes and risk of colorectal cancer Title Genetická variace u adipokinových genů a riziko kolorektálního karcinomu Author(s) Pechlivanis, S. (DE)
Bermejo, J. L. (DE)
Pardini, Barbara (UEM-P)
Naccarati, Alessio (UEM-P)
Vodičková, Ludmila (UEM-P) RID
Novotný, J. (CZ)
Hemminki, K. (SV)
Vodička, Pavel (UEM-P) RID
Försti, A. (DE)Source Title European Journal of Endocrinology - ISSN 0804-4643
Roč. 160, č. 6 (2009), s. 933-940Number of pages 8 s. Language eng - English Country DK - Denmark Keywords colorectal cancer ; diabetes Subject RIV EB - Genetics ; Molecular Biology R&D Projects GA310/07/1430 GA ČR - Czech Science Foundation (CSF) NR8563 GA MZd - Ministry of Health (MZ) CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000272934600007 DOI 10.1530/EJE-09-0039 Annotation Obesity has been related to an increased risk of colorectal cancer (CRC). Adipokines produced by the adipose tissue are directly linked to obesity and may thus contribute to the pathogenesis of CRC. Our results suggest that variants in the adipokine genes may affect CRC risk in combination with variants in diabetes-related genes. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2010
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