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Cardiac stem/progenitor cells, secreted proteins, and proteomics
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SYSNO ASEP 0325072 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Cardiac stem/progenitor cells, secreted proteins, and proteomics Title Kmenové buňky srdce, vylučované proteiny a proteomika Author(s) Šťastná, Miroslava (UIACH-O) RID, ORCID
Abraham, M.R. (US)
Van Eyk, J.E. (US)Source Title FEBS Letters. - : Wiley - ISSN 0014-5793
Roč. 583, č. 11 (2009), s. 1800-1807Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords Cardiac stem/progenitor cell ; paracrine factor ; secretome Subject RIV EB - Genetics ; Molecular Biology CEZ AV0Z40310501 - UIACH-O (2005-2011) DOI 10.1016/j.febslet.2009.03.026 Annotation There is a small population of resident stem cells in adult heart from which new cardiac cells can be derived and used for cardiac repair in case of heart injury. It has been proposed that the clinical benefit of stem cells may arise from secreted proteins that mediate regeneration in a paracrine/autocrine manner. To be able to track the regulatory pathway on a molecular basis, utilization of proteomics in stem cell research is essential. Proteomics offers a tool that can address questions regarding stem cell response to disease/injury. Workplace Institute of Analytical Chemistry Contact Iveta Drobníková, drobnikova@iach.cz, Tel.: 532 290 234 Year of Publishing 2009
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