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Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX
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SYSNO ASEP 0323910 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX Title Úloha receptoru pro aromatické uhlovodíky v modulaci exprese hypoxického markeru karbonické anhydrázy IX Author(s) Takáčová, M. (SK)
Holotňáková, T. (SK)
Vondráček, Jan (BFU-R) RID, ORCID
Machala, M. (CZ)
Pěnčíková, K. (CZ)
Gradin, K. (SE)
Poellinger, L. (SE)
Pastorek, J. (SK)
Pastoreková, S. (SK)
Kopáček, J. (SK)Source Title Biochemical Journal. - : Portland Press - ISSN 0264-6021
Roč. 419, - (2009), s. 419-425Number of pages 7 s. Language eng - English Country GB - United Kingdom Keywords AhR ; carbonic anhydrase IX ; dioxin Subject RIV BO - Biophysics CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000265196900018 DOI 10.1042/BJ20080952 Annotation The results from the present study suggest that treatment with, an AhR ligand, reduces hypoxic induction of both CA IX mRNA and protein expression. ARNT is critical for both hypoxic induction and the TCDD-mediated inhibition of CA IX expression. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2009
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