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Adaptation of breast cancer cells to glucose deprivation: Increase in capacity and affinity of the oxphos system
- 1.0321502 - FGÚ 2009 NL eng A - Abstract
Smolková, Katarína - Bellance, N. - Benard, G. - Letellier, T. - Gnaiger, E. - Hlavatá, Lydie - Ježek, Petr - Rossignol, R.
Adaptation of breast cancer cells to glucose deprivation: Increase in capacity and affinity of the oxphos system.
[Adaptace buněk rakoviny prsu na nedostatek glukózy: Zvýšení kapacity a afinity oxfos systému.]
Biochimica Et Biophysica Acta-Bioenergetics. Elsevier. Roč. 1777, Suppl. (2008), S80-S80. ISSN 0005-2728. E-ISSN 1879-2650.
[European Bioenergetics Conference /15./. 19.07.2008-24.07.2008, Dublin]
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpo1 * glucose deprivation * oxphos system
Subject RIV: ED - Physiology
The aim of this tudy was to investigate the adaptation of cancer cells to low glucose conditions, as regard to their mitochondrial features. In cancer cells, glucose deprivation lead to a change in p50 value. There was also a 2 to 3-fold increase in routine respiration in glucose versus galactose medium
Účelem této studie bylo zjistit adaptaci rakovinných buněk na nízkou koncentraci glukózy. V těchto buňkách deprivace glukózy vedla ke změně hodnoty p50. Také bylo rovněž pozorováno 2 - 3-násobné zvýšení rutinní respirace ať už v glukózovém nebo galaktózovém médiu
Permanent Link: http://hdl.handle.net/11104/0170013
Number of the records: 1