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Late blood pressure reduction in shr subjected to transient captopril treatment in youth: possible mechanisms

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    SYSNO ASEP0310364
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleLate blood pressure reduction in shr subjected to transient captopril treatment in youth: possible mechanisms
    TitlePozdní snížení krevního tlaku u spontánně hypertenzních potkanů vystavených přechodnému podávání kaptoprilu v mládí: možné mechanismy
    Author(s) Zicha, Josef (FGU-C) RID, ORCID, SAI
    Dobešová, Zdenka (FGU-C)
    Kuneš, Jaroslav (FGU-C) RID, ORCID
    Source TitlePhysiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
    Roč. 57, č. 3 (2008), s. 495-498
    Number of pages4 s.
    Languageeng - English
    CountryCZ - Czech Republic
    Keywordscaptopril ; nifedipine ; late effects of early treatment
    Subject RIVFA - Cardiovascular Diseases incl. Cardiotharic Surgery
    R&D Projects1M0510 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    GA305/08/0139 GA ČR - Czech Science Foundation (CSF)
    CEZAV0Z50110509 - FGU-C (2005-2011)
    UT WOS000257270900024
    AnnotationOur study was aimed to elucidate the mechanisms responsible for long-term persistence of blood pressure reduction after early blockade of angiotensin II formation by captopril. It was found that blood pressure reduction was caused by attenuation of sympathetic vasoconstriction (sensitive to nifedipine) and by lowering of residual blood pressure (reflecting structural alterations of resistance vessels)
    WorkplaceInstitute of Physiology
    ContactLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Year of Publishing2009
Number of the records: 1  

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