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Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands
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SYSNO ASEP 0305777 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands Title Syntéza, biofyzikální studie a protinádorová aktivita platnatých komplexů obsahujících 1,2-bis(amino methyl)karbobicyklické ligandy Author(s) de Mier-Vinué, J. (ES)
Gay, M. (ES)
Montana, Á.M. (ES)
Sáez, R.-I. (ES)
Moreno, V. (ES)
Kašpárková, Jana (BFU-R) RID, ORCID
Vrána, Oldřich (BFU-R) RID
Heringová, Pavla (BFU-R)
Brabec, Viktor (BFU-R) RID, ORCID
Boccarelli, A. (IT)
Coluccia, M. (IT)
Natile, G. (IT)Source Title Journal of Medicinal Chemistry. - : American Chemical Society - ISSN 0022-2623
Roč. 51, č. 3 (2008), s. 424-431Number of pages 8 s. Language eng - English Country US - United States Keywords DNA ; platinum ; cancer Subject RIV BO - Biophysics R&D Projects GA305/05/2030 GA ČR - Czech Science Foundation (CSF) NR8562 GA MZd - Ministry of Health (MZ) 1QS500040581 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) LC06030 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) Annotation This work describes the synthesi, DNA interactions and antitumor activity in vitro of platinum(II) complexes having 1,2-bis(amino methyl)carbobicyclic ligands. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2008
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