Synthesis of new oxytocin analogues with high antagonistic activity
1.
SYSNO ASEP
0194930
Document Type
C - Proceedings Paper (int. conf.)
R&D Document Type
Conference Paper
Title
Synthesis of new oxytocin analogues with high antagonistic activity
Author(s)
Fragiadaki, M. (GR) Bissyris, E. (GR) Magafa, V. (GR) Slaninová, Jiřina (UOCHB-X) Cordopatis, P. (GR)
Source Title
Collection Symposium Series 6 / Slaninová J.. - Praha : ÚOCHB AV ČR, 2003
- ISBN 80-86241-20-3
Pages
s. 26-28
Number of pages
3 s.
Action
Biologically Active Peptides /8./
Event date
23.04.2003-25.04.2003
VEvent location
Praha
Country
CZ - Czech Republic
Event type
EUR
Language
eng - English
Country
CZ - Czech Republic
Keywords
oxytocin ; oxytocin antagonists ; D-cysteine
Subject RIV
CE - Biochemistry
CEZ
AV0Z4055905 - UOCHB-X
Annotation
The synthesis of new OT analogues bearing the following modifications: L-ŕ-t-butylglycine [Gly(Bu')] at positions 8 and 9, D-Cys and D-Tyr(Et) at positions 6 and 2, respectively, and Mpa or Pen at position 1 have been described.
