0194809 - UOCHB-X 20030115 RIV CZ eng J - Journal Article
Trtek, T. - Černý, M. - Trnka, T. - Buděšínský, Miloš - Císařová, I.
Synthesis of tricycles based on 1,6-anhydro-á-D-hexopyranoses fused with morpholine. 3,10,12-trioxa-6-azatricyclo[7.2.1.0 2,7 ]dodecanes.
Collection of Czechoslovak Chemical Communications. Roč. 68, č. 7 (2003), s. 1295-1308. ISSN 0010-0765
Institutional research plan: CEZ:AV0Z4055905
Keywords : carbohydrates * heterocycles * conformation analysis
Subject RIV: CC - Organic Chemistry
Impact factor: 1.041, year: 2003

The opening of the oxirane ring in 1,6:3,4-dianhydro-2-OTos-á-D-Galwith 2-chloroethanol gave 1,6-anhydro-4-O-(2-chloroethyl)-2-OTos-á-D-Glc, which was converted in 4 steps into 4-O-(2-aminoethyl)-1,6,2,3-dianhydro-á-D-Man. Its intramolecular cyclisation afforded the fused morpholine derivative.
Permanent Link: http://hdl.handle.net/11104/0090480