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5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines - acyclic nucleoside phosphonate analogues with antiviral activity

  1. 1.
    SYSNO ASEP0194796
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    Title5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines - acyclic nucleoside phosphonate analogues with antiviral activity
    Author(s) Hocková, Dana (UOCHB-X) RID, ORCID
    Holý, Antonín (UOCHB-X)
    Masojídková, Milena (UOCHB-X)
    Andrei, G. (BE)
    Snoeck, R. (BE)
    De Clercq, E. (BE)
    Balzarini, J. (BE)
    Source TitleJournal of Medicinal Chemistry. - : American Chemical Society - ISSN 0022-2623
    Roč. 46, - (2003), s. 5064-5073
    Number of pages10 s.
    Languageeng - English
    CountryUS - United States
    Keywordspyrimidines ; antivirals ; nucleotide analogues
    Subject RIVCC - Organic Chemistry
    R&D ProjectsKSK4055109 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZAV0Z4055905 - UOCHB-X
    Annotation5-Allyl, 5-benzyl, 5-cyanomethyl, 5-ethoxycarbonylmethyl, 5-phenyl, 5-cyclopropyl, 5-methyl, 5-chloro and 5-bromo-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines were prepared and their antiviral activity was evaluated.
    WorkplaceInstitute of Organic Chemistry and Biochemistry
    Contactasep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
    Year of Publishing2004

Number of the records: 1  

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