0194791 - UOCHB-X 20030097 RIV US eng J - Journal Article
Barabás, O. - Rumlová, Michaela - Erdei, A. - Pongrácz, V. - Pichová, Iva - Vértessy, B. G.
dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency.
Journal of Biological Chemistry. Roč. 278, č. 40 (2003), s. 38803-38812. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA AV ČR IAA4055304
Grant - others:HNRF(HU) T034120; HNRF(HU) TS044730; HNRF(HU) M27852; HHMI(US) 55000342
Institutional research plan: CEZ:AV0Z4055905
Keywords : dUTPase * M-PMV * pyrophosphatase
Subject RIV: CE - Biochemistry
Impact factor: 6.482, year: 2003

We demonstrate that Mason-Pfizer monkey virus dUTPase, exists as a fusion protein NC-dUTPase both within the virions and infected cells and provides the only form of dUTPase. We show that recombinant beteretroviral NC-dUTPase and dUTPase are both inefficient catalysts compared to all other dUTPases.
Permanent Link: http://hdl.handle.net/11104/0090462