0194408 - UOCHB-X 20020074 RIV GB eng J - Journal Article
Harmatha, Juraj - Buděšínský, Miloš - Vokáč, Karel
Photochemical transformation of 20-hydroxyecdysone: production of monomeric and dimeric ecdysteroid analogues.
Steroids. Roč. 67, - (2002), s. 127-135. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA ČR GA203/98/0451; GA MŠMT LB98233
Institutional research plan: CEZ:AV0Z4055905
Keywords : ecdysteroid
Subject RIV: CC - Organic Chemistry
Impact factor: 2.524, year: 2002

Photochemical transformation of 20-hydroxyecdysone (20E) yielded a dimeric ecdysteroid as a main product. Its structure was determined by detailed NMR analysis. Two new monomeric analogues were also identified. The transformed dimeric analogue of 20E retained the high agonistic activity on the ecdysone receptor in the B-II bioassay.
Permanent Link: http://hdl.handle.net/11104/0090083