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-H.sub.2./sub.-lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart
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SYSNO ASEP 0194237 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title -H2-lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart Author(s) Hanuš, J. (CZ)
Barvík, I. (CZ)
Ruszová-Chmelová, K. (CZ)
Štěpánek, J. (CZ)
Turpin, P. Y. (FR)
Bok, J. (CZ)
Rosenberg, Ivan (UOCHB-X) RID, ORCID
Endová, Magdalena (UOCHB-X) RID, ORCIDSource Title Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048
Roč. 29, č. 24 (2001), s. 5182-5194Number of pages 13 s. Language eng - English Country GB - United Kingdom Keywords phosphonate internucleotide linkage Subject RIV CC - Organic Chemistry R&D Projects IAA4055902 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA203/01/1166 GA ČR - Czech Science Foundation (CSF) VS97113 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z4055905 - UOCHB-X Annotation The complete family of ApA phosphonate analogues with the internucleotide linkage elongated by insertion of a -CH2- group was prepared and the hybridisation and structural properties of its members in interaction with polyuridylic acid were investigated using an original 2D Raman approach. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2002
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