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Synthesis and cytostatic activity of .I.N./I.-[2-(phosphonomethoxy)alkyl]derivatives of .I.N./I..sup.6./sup.-substituted adenines, 2,6-diaminopurines and related compounds
- 1.0194131 - UOCHB-X 20010214 RIV CZ eng J - Journal Article
Holý, Antonín - Votruba, Ivan - Tloušťová, Eva - Masojídková, Milena
Synthesis and cytostatic activity of .I.N./I.-[2-(phosphonomethoxy)alkyl]derivatives of .I.N./I.6-substituted adenines, 2,6-diaminopurines and related compounds.
Collection of Czechoslovak Chemical Communications. Roč. 66, č. 10 (2001), s. 1545-1592. ISSN 0010-0765
R&D Projects: GA ČR GV203/96/K001; GA MZd NL5423; GA AV ČR IBS4055109
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * nucleotide analogs
Subject RIV: CC - Organic Chemistry
Impact factor: 0.778, year: 2001
..I.N./I.6-Substituted adenine and 2,6-diaminopurine derivatives of 9-[2-phosphonomethoxy)ethyl] and 9-[(.I.R./I.)-2-(phosphonomethoxy)propyl] series were synthesized by reactions of amines with 6-chloro-9-{[2-(diisopropoxyphosphoryl)methoxy]alkyl}purines.
Permanent Link: http://hdl.handle.net/11104/0089822
Number of the records: 1