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Synthesis of normuramic acid carba analog and its glycopeptide derivative resistant to á-elimination splitting of the side chain

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    0193838 - UOCHB-X 20000300 RIV CZ eng J - Journal Article
    Ledvina, Miroslav - Kovaříková, Radka - Rohlenová, Anna - Ježek, Jan - Šaman, David
    Synthesis of normuramic acid carba analog and its glycopeptide derivative resistant to á-elimination splitting of the side chain.
    Collection of Czechoslovak Chemical Communications. Roč. 65, č. 11 (2000), s. 1726-1736. ISSN 0010-0765
    R&D Projects: GA ČR GA203/96/0309; GA MŠMT LB98233; GA MPO PZ-Z2/25
    Institutional research plan: CEZ:AV0Z4055905
    Subject RIV: CC - Organic Chemistry
    Impact factor: 0.960, year: 2000

    Synthesis of muramyl glycopeptides carba analogs having the side chain linking to C-3 of their saccharide unit with C-C bond. Key carba analogs of normuramic acid, i.e., 3-(2-acetamido-2,3-dideoxy-D-glucopyranos-3-yl)propanoic acid derivatives were prepared by addition of radicals generated from appropriate 3-O-thiocarbonyl derivatives of N-acetyl-D-glucosamine with Bu3SnH to acrylic acid derivatives.
    Permanent Link: http://hdl.handle.net/11104/0089530
     

Number of the records: 1  

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