Two dynamic morphotypes of sarcoma cells, asymmetric stellate and triangle with leading lamella, are related to malignancy
1.
SYSNO ASEP
0191553
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Two dynamic morphotypes of sarcoma cells, asymmetric stellate and triangle with leading lamella, are related to malignancy
Author(s)
Pokorná, Eva (UMG-J) Zicha, D. (GB) Chaloupková, Alena (UMG-J) Matoušková, Eva (UMG-J) Veselý, Pavel (UMG-J)
Source Title
Folia Biologica. - : Univerzita Karlova v Praze
- ISSN 0015-5500
Roč. 49, č. 1 (2003), s. 33-49
Number of pages
17 s.
Language
eng - English
Country
CZ - Czech Republic
Keywords
morphotypes ; stellate ; lamella
Subject RIV
EB - Genetics ; Molecular Biology
R&D Projects
GA304/99/0368 GA ČR - Czech Science Foundation (CSF)
CEZ
AV0Z5052915 - UMG-J
Annotation
A notion of the dynamic morphotype was developed as a conjunction between cel shape and migration. This enabled the investigation of the relationship between malignancy ond patterns of dynamic morphology in neoplastic cell lines (K2, T15, and A8), differing in metastatic potential, that were instrumental in revealing a coincidence between high migratory activity and appearance of the 3D structure of actin cebles in high-malignant A8 cells (Pokorná et al., 1994).
