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Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms
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SYSNO ASEP 0191464 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms Author(s) Mendoza, Luis (UMG-J)
Bubeník, Jan (UMG-J)
Šímová, Jana (UMG-J) RID
Korb, Jan (UMG-J)
Bieblová, Jana (UMG-J)
Vonka, V. (CZ)
Indrová, Marie (UMG-J) RID
Mikyšková, Romana (UMG-J) RID
Jandlová, Táňa (UMG-J)Source Title Folia Biologica. - : Univerzita Karlova v Praze - ISSN 0015-5500
Roč. 48, č. 3 (2002), s. 114-119Number of pages 6 s. Language eng - English Country CZ - Czech Republic Keywords HPV 16 ; dendritic cells ; adjuvant therapy Subject RIV EB - Genetics ; Molecular Biology R&D Projects NC7148 GA MZd - Ministry of Health (MZ) GA301/00/0114 GA ČR - Czech Science Foundation (CSF) IAA7052002 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) IAA5052203 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z5052915 - UMG-J Annotation It was examined whether administration of APC at the site od HPV 16-associated tumours can inhibit their growth and whether the efficacy of esteblished DC lines is comparable to that of fresh BMDC. The result suggest that local increase in the number of DC can inhibit progression of tumours and that DC may be used for delivery of therapeutic vaccines against HPV 16 neoplasms. The efficacy of established lines and fresh DC was comparable. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2003
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