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Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody
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SYSNO ASEP 0191346 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody Author(s) Řezáčová, Pavlína (UMG-J) RID
Lescar, J. (FR)
Brynda, Jiří (UMG-J) RID
Fábry, Milan (UMG-J) RID
Hořejší, Magdalena (UMG-J)
Sedláček, Juraj (UMG-J) RID
Bentley, G. (FR)Source Title Structure. - : Cell Press - ISSN 0969-2126
Roč. 9, č. 10 (2001), s. 887-895Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords single-chain Fv ; cross-reactivity ; HIV protease Subject RIV EB - Genetics ; Molecular Biology R&D Projects IAA5052502 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GV203/98/K023 GA ČR - Czech Science Foundation (CSF) Annotation Since the demonstration that the protease of the human immunodeficiency virus (HIV Pr) is essential in the viral life cycle, this enzyme has become one of the primary targets for antiviral drug design. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2002
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